Born in Kaohsiung, Wen-chen Chuang has shown her great talent in music since she was in grade school. As a student, she has won many great prizes in piano performance, composition and violin performance from city-wide and nation-wide competitions. In 1990, Wen-chen's excellent performance in music earns her the admission from the top-ranked music school of Taiwan, the Department of Music of National Taiwan Normal University (NTNU). She received her bachelor degree in 1994 and then served as the 1st violinist in Kaohsiung City Symphony Orchestra.

In 1996, she entered the master program in conducting from NTNU and started to conduct several student orchestras.

In 1997, Wen-chen received a scholarship from Taiwan-Austria joint study program to study orchestral conducting in Universität für Musik und darstellende Kunst Wien under the supervise of Prof. Uros Lajovic. Her great performance in Vienna wins her many opportunities to conduct with Vienna Pro Arte Orchestra and Philharmonic Orchestra of Oradea. In 2002 and 2003, Wen-chen conducted with Vienna Taiwan Youth Orchestra in the annual national day concerts in Musikverein and Konzerthaus, two of the most famous concert halls in Vienna. Later in 2003 she won the conducting-concert prize in the International Master Classes Summer on Vienna.

Wen-chen Chuang is currently resident conductor of Evergreen Symphony Orchestra and also the conductor of National Taiwan University Symphony Orchestra. She has performed at Taipei National Concert Hall, Tokyo International Forum , Los Angeles and Shanghai Concert Hall and cooperated with the pianist, Alexei Volodin, Alexander Gavrylyuk, Yukio Yokoyama, Weiyin Chen, Rueibin Chen, Eric Chen, Fan-Chiang Yi, Shih-Wei Chen, Chiao-Han Liao, Kuan-Ting Lin, Chun-Chieh Yen, Gwhyneth Chen; flutist, Gary Schocker, Amy Porter, Vincent Lucas, Andrea Lieberknecht, Sophie Cherrier, Seiya Ueno, Hu Chih-Wei, Lorna McGhee, Andrea Oliva; violinist, Si-Qing Lu, Hina Maeda, Su Shien-Da, Richard Lin, Ching-Ting Chang etc. She worked also as a guest conductor with Croatia HRT Symphony Orchestra, Kaohsiung City Symphony Orchestra and Kaohsiung City Chinese Orchestra. The audience is fond of and moved by her fresh, sentimental and stylish way of conducting.